RYR2 channel inhibition is the principal mechanism of flecainide action in CPVT
- Creator: Kryshtal, Dmytro O. , Blackwell, Daniel J. , Egly, Christian L. , Smith, Abigail N. , Batiste, Suzanne M. , Johnston, Jeffrey N. , Laver, Derek R. , Knollmann, Bjorn C.
- Resource Type: journal article
- Date: 2021
Mechanisms of cardiac ryanodine receptor inhibition by anti arrhythmic drugs
- Creator: Mehra, Divya Rajendra
- Resource Type: thesis
- Date: 2014
Multiple modes of ryanodine receptor 2 inhibition by flecainide
- Creator: Mehra, D. , Imtiaz, M. S. , van Helden, D. F. , Knollmann, B. C. , Laver, D. R.
- Resource Type: journal article
- Date: 2014
Inhibition of cardiac Ca²⁺ release channels (RyR2) determines efficacy of class I antiarrhythmic drugs in catecholaminergic polymorphic ventricular tachycardia
- Creator: Hwang, Hyun Seok , Hasdemir, Can , Laver, Derek , Mehra, Divya , Turhan, Kutsal , Faggioni, Michela , Yin, Huiyong , Knollmann, Björn C.
- Resource Type: journal article
- Date: 2011
Flecainide inhibits arrhythmogenic Ca²⁺ waves by open state block of ryanodine receptor Ca²⁺ release channels and reduction of Ca²⁺ spark mass
- Creator: Hilliard, Fredrick A. , Steele, Derek S. , Laver, Derek , Yang, Zhaokang , Le Marchand, Sylvain J. , Chopra, Nagesh , Piston, David W. , Huke, Sabine , Knollmann, Björn C.
- Resource Type: journal article
- Date: 2010